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Gabriele Sadowski (TUD), Sarah Hudson (UL), Philippe Fernandes (Janssen) Eligibility Criteria: MSc in chemical engineering or physical chemistry; Applicants must not have resided or carried out their main activity in Germany for more than 12 months in the 3 years immediately before the date of application. Limerick . These cookies allow us to count visits and traffic sources, so we can measure and improve the performance of our site. *Corresponding author: Sarah.Hudson@ul.ie 10 Abstract Nanoparticles of poorly water-soluble drugs were prepared in suspension via antisolvent precipitation in order to improve their dissolution behaviour. My research focuses on the control of nucleation of organic pharmaceutical molecules and the development of crystallisation technologies to improve the bioavailability of such molecules. This research will develop biocatalysts using immobilised enzymes for synthetic and medical applications. See more of Sarah Hudson - Liberty on Facebook. Sarah has 4 jobs listed on their profile. OVERALL PURPOSE OF THE JOB: To establish processes and procedures that will develop the SFI funded Bernal BioLabs BioProcess infrastructure testbed into a self-sustainable facility with independent projects, future proofing the operation of the facility and the translation of research between academia and industry and to engage in the development of methods and knowledge on Prof. Michael HB Hayes. Sarah Mallen B.Sc. We use cookies to give you the best online experience. After this fellowship, I worked in Waterford Institute of Technology on the identification of the mechanisms and causes of tablet splitting within the Genzyme Ireland Ltd. facility. Submicron to small-micron-sized particles of the hydrophobic drug, fenofibrate, were prepared by controlled crystallization in order to influence its dissolution behavior. These cookies are necessary for the website to function and cannot be switched off in our systems. _____ Sarah Mallen . She currently supervises 8 PhD students, 4 postdoctoral researchers and 2 research assistants. Qualifications. Their research focuses on the thermodynamics behind aggregation, crystallisation and precipitation in a range of solvents and bio relevant media and develops formulations to control this solution/solid-state behaviour. ii Acknowledgements . The Journal of Physical Chemistry B 109 (41), 19496-19506 Department of Chemical and Environmental Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, Co. View Sarah Hudson’s profile on LinkedIn, the world’s largest professional community. Submitted to the University of Limerick, April 2017 . LongActNow will deliver industrially-informed, interdisciplinary training to five Early Stage Researchers (ESRs) in relevant areas of expertise including crystallisation, solution behaviour modelling and solvent switching, pharmacokinetics and formulation. In order to use this website we use the following technically required cookies. For perfomance reasons we use Cloudflare as a CDN network. CONTACT. We prioritise talent development to support our people to become national and global influencers in their field. SP Hudson, RF Padera, R Langer, DS Kohane HPLC, UV-vis and FTIR V94 T9PX . University of Limerick . PMID: 30579056 DOI: 10.1016/j.colsurfb.2018.12.021 Abstract Drug nanoparticles are a promising solution to the challenging issues of low dissolution rates and erratic bioavailability due to their greater surface/volume ratio. Our Early Stage Researchers & Supervisors. Sarah Hudson (UL) Read More » Supervisors. She was awarded a masters in Chemistry from Trinity a year later, where she worked on the photophysical properties of rhenium complexes with Prof John Kelly. Biomaterials 29 (30), 4045-4055 Search for more papers by this author. PMID: 27884714 DOI: 10.1016/j.ijpharm.2016.11.045 Abstract Nanoparticles of poorly water-soluble drugs were prepared in suspension via antisolvent precipitation in order to improve their dissolution behaviour. J. Gerard Wall NUI Galway … SSPC University of Limerick Bernal Institute Castletroy. Department of Chemical Sciences, Bernal Institute, University of Limerick, Limerick, Ireland. 137 Co-reductive fabrication of carbon nanodots with high quantum yield for bioimaging of bacteria Jiajun€Wang1, Xia€Liu1, Gesmi€Milcovich2, Tzu-Yu€Chen3, Edel€Durack2, Sarah€Mallen2, Yongming€Ruan1, Xuexiang€Weng*1 and€Sarah€P.€Hudson*2 Full Research … Biocatalysis Co. by research in Chemistry, Trinity College Dublin. Biography Sarah studied Chemistry in Trinity College Dublin were she was a Trinity Foundation Scholar and where she did a research masters on the synthesis of a family of Re (I) metal complexes and a study of their photophysical properties with Prof John Kelly. We study the effects of the components bio-relevant media on the solution and crystallisation behaviour of active pharmaceutical ingredients in vitro – quantifying drug-component interactions and their influence on nucleation and crystallisation events. Deadline for applications is 15 June 2020, 5pm (Irish Standard Time). The biocompatibility (in vivo and in vitro) of micro- and nano- mesoporous silica particles was also studied. Sarah Hudson Dr. E-mail address: sarah.hudson@ul.ie. (Read more. E-mail: sarah.hudson@ul.ie. Limerick . Specialist Diploma in Teaching, Learning and Scholarship, Ph.D. Chemistry University of Limerick. sarah.hudson@ul.ie Keywords: Mesoporous matrices; Nisin A; Controlled release; Antimicrobial; periodic mesoporous organosilanes; simulated gastrointestinal fluid; bacteriocins Abstract Mesoporous matrices of different pore size and chemical composition were explored as potential delivery matrices for the broad spectrum bacteriocin, nisin A. Control your personal Cookie Services here. Pictured with MIT’s Professor Robert Langer on his recent visit to UL to deliver the second in the Bernal Distinguished Lecture Series, is Dr Sarah Hudson. The awardees are Bernal Institute Members and SSPC Researchers, Dr Sarah Hudson and Dr Luis Padrela, UL Chair of Mechanical Engineering, Professor Noel O’Dowd, along with Dr Norma Bargary of UL’s Department of Mathematics and Statistics, who will work with Andrew Simpkin … David Murray. UL will receive close to €2m in research funding under the programme for four projects based at the University. She was awarded a masters in Chemistry from Trinity a year later, where she worked on the photophysical properties of rhenium complexes with Prof John Kelly. Supervisor: Dr. Sarah Hudson . The Hudson research group focuses on the manipulation of the physicochemical properties of small and large active molecules to improve their stability, solubility and dissolution rates with the ultimate goal of improving the bioavailability of active pharmaceutical ingredients. Other research interests include bioprocessing, biocatalysis and drug delivery. When you visit any web site, it may store or retrieve information on your browser, mostly in the form of cookies. (Mod) in Chemistry, Trinity College Dublin. Qualified PRINCE2 Practitioner in project management. Thermal analysis (TGA, DSC) I would also like to thank the other members of our research group, Edel and James, for making UL an enjoyable place to be. Angewandte Chemie International Edition 47 (45), 8582-8594 Specialist Diploma in Teaching, Learning and Scholarship, Ph.D. Chemistry University of Limerick. We functionalise materials to tailor the immobilisation of enzymes to generate biocatalysts with optimal activity and stability. Using crystallisation approaches or delivery matrices (polymeric or ceramic), we seek to maximise the bioavailability and activity of these molecules in vivo and reduce the cost of their development into medicines. Ireland . Since November 2011, Sarah has been a lecturer in Chemistry in the Department of Chemical Sciences and a researcher in the Bernal Institute in the University of Limerick. Following a sabbatical from academia spent working as a raft guide and safety kayaker on 3 continents, I completed my PhD in 2006 on the immobilization of enzymes onto novel mesoporous supports and their catalytic properties in the University of Limerick. Lacticin 3147 is a dual-acting two-peptide bacteriocin which is generally active against Gram-positive bacteria, including Listeria monocytogenes and antimicrobial-resistant bacteria such as Closteroides difficile in the colon. Since November 2011, I have been a lecturer in Chemistry in the Department of Chemical Sciences and a researcher in the Bernal Institute in the University of Limerick. Project Details. Limerick . Sarah Hudson Dr. sarah.hudson@ul.ie; Department of Chemical and Environmental Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, Co. Proteins in mesoporous silicates Researchers from around Ireland gathered in University of Limerick (UL) on Friday morning to listen to one of the world’s top engineers discuss his work in the area of biomaterials and biotechnology. This work focuses on the improvement of drug bioavailablilty by crystal engineering approaches, by using ceramics and synthetic polymers as delivery vehicles and by exercising control over crystal growth of sub-micron nanocrystals of poorly water soluble drugs. sarah.hudson@ul.ie . Research and Teaching Interests. She is a funded investigator in the Synthesis and Solid State Pharmaceutical Research Centre (SSPC) since 2013. Anke Prudic-Paus (Janssen) Read More » Supervisors. Rene Holm (Janssen), Sarah Hudson (UL), Lidia Tajber (TCD) Eligibility Criteria: Minimum BSc in chemical engineering, physical chemistry or related discipline; Applicants must not have resided or carried out their main activity in Belgium for more than 12 months in the 3 years immediately before the date of application. Search for more papers by this author. Jakki Cooney Dr. Department of Life Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, … This saves a cookie "__cfduid" to apply security settings on a per-client basis. I will be forever grateful for all her help, anything I achieve will be thanks to the mentoring I received from you during the last four years. Sarah Hudson is currently signed to Prescription Songs/AAM as a songwriter. • View Journal Article, The biocompatibility of mesoporous silicates Email: tewfik.soulimane@ul.ie (T. S.) and Email: sarah.hudson@ul.ie (S. P. H.) Search for more papers by this author. Nucleation and particle growth, release kinetics, bioavailability. An antisolvent precipitation process successfully generated particles (200–300 nm) which matched the size and dissolution behavior of a commercial wet-milled formulation of the drug. My research is divided into two main strands: Drug formulation and delivery I was also responsible for the installation and use of a solid state NMR system. Electronic address: Sarah.Hudson@ul.ie. By agreeing you accept the use of cookies in accordance with our cookie policy. Dr Sarah Hudson, Department of Chemical Sciences, Bernal Insitute, University of Limerick Sarah graduated from Trinity College Dublin in 1999 as a Trinity Foundation Scholar. They explore the solution and solid-state behaviour of these molecules both during formulation/manufacture into medicines and in biorelevant environments. B.A. We track anonymized user information to improve our website. • View Journal Article, Methodology for the immobilization of enzymes onto mesoporous materials Limerick V94 T9PX. Office: MS2-019, 4 Synthesis and Solid State Pharmaceutical Centre, Department of Chemical Sciences, The Bernal Institute, University of Limerick, Limerick, V94 T9PX, Ireland. A song she co-wrote with Katy Perry, Dr. Luke, Max Martin and Cirkut entitled "Dark Horse" became Perry's third single off her album, Prism. Her subsequent postdoctoral studies were spent with Prof Robert Langer at Massachusetts Institute of Technology in Boston and Dr Peter McLoughlin at Waterford Institute of Technology, Ireland where she moved into the field of drug delivery and pharmaceutical manufacturing. Jakki Cooney Dr. Department of Life Sciences, Materials and Surface Science Institute, University of Limerick, Plassey, Co. This cookie is strictly necessary for Cloudflare's security features and cannot be turned off. Project Details. I studied Chemistry in Trinity College Dublin which led to a research masters on the synthesis of a family of Re (I) metal complexes and a study of their photophysical properties. L. monocytogenes infections can cause life-long effects in the elderly a … Search for more papers by this author. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 861278. Dr Sarah Hudson, Department of Chemical Sciences, Bernal Insitute, University of Limerick. We examine the factors that influence the optimisation of mammalian and microbial fermentation processes for the production of small and large molecules. She is the project coordinator for LongActNow and project leader on a Disruptive Technology Innovation Award on the development of enzymes as therapeutics. "Dark Horse" has been a commercial success, charting at number one on the US Billboard Hot 100. Open, Transparent, Merit based Recruitment procedures of Researchers (OTM-R) Know more about it at … Yina Guo Researcher, University of Limerick Verified email at ul.ie. Sarah graduated from Trinity College Dublin in 1999 as a Trinity Foundation Scholar. Closing Date: 17:00 Friday, 14-May-2021 Position: In both of these research strands, the following analytical techniques are heavily relied upon: Solid state NMR, X-ray diffraction S Hudson, J Cooney, E Magner Search for more papers by this author. by research in Chemistry, Trinity College Dublin. I declare that this thesis is entirely my own work and has not been previously submitted to this or any other university. Adjunct Prof. Chemistry of the Colloids in Soils and Waters. University of Limerick. MSSI Building, i Declaration . One main target application is in the formulation of new drugs to treat antimicrobial resistant infections. See the complete profile on LinkedIn and discover Sarah’s connections and jobs at similar companies. COOK Ireland Limited, Limerick, Ireland . Sarah is a Materials theme leader and funded investigator in the SSPC. Horse '' has been a commercial success, sarah hudson ul at number one the! 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